TB test (Getty Images/ Jaruno11)

Novel molecular tests are gaining popularity as a rapid way to detect genetic mutations that render tuberculosis impervious to drugs. Yet, how well these new tests fare in gauging risk of actual drug failure and patient death has remained unclear.

Mycobacterium tuberculosis bacteria (CDC 2006)

A mathematician and a pulmonologist walk into a bar…

Photo: Nattul, Getty Images

Call it the “too much knowledge” paradox: The vast amount of new data generated by biomedical science carries the promises to make medicine über-precise. In the meantime, however, it does so at the peril of generating too much noise and confusion.

Large crowd fading into distance, representing concept of population over time

The survival of the human species in the face of a high number of incoming genetic mutations has remained an important problem in evolutionary biology. A newborn human is estimated to receive about 70 new mutations that the parents did not have.

Drug repositioning, or putting already approved compounds to new uses, has gained ground in recent years as a cost-saving alternative to traditional drug development.

The Department of Biomedical Informatics at Harvard Medical School has named Bill Geary to its advisory council.

Congratulations, Peter -- butter cream cake with strawberries

Undergrad trainees often inquire how best to trek the pathway to academic success.

sleeping pills next to clock in the wee hours

Clinical decision-making is a complex process, driven by multiple factors, including social and psychological dynamics, peer pressure and even exposure to drug advertising.

Parasitic wasp from Parasite Award website (Image CC-BY-SA by berniedup)

A DBMI postdoctoral research fellow has been honored with a Parasite Award, recognizing his outstanding contribution to the rigorous secondary analysis of data.

New Seminar Series Within Sight

We are excited to announce the launch of Open Insights, a series of research talks related to the mission of DBMI. This interdisciplinary seminar provides an open forum to engage participants in a discussion about the future of quantitative methods and engineering in biomedicine.