Cartik Ram Kothari Saravanamuthu, Ph.D.
Cartik Ram Kothari Saravanamuthu, Ph.D.
Data Scientist in Biomedical Informatics

Cartik Saravanamuthu holds a Ph.D. in computer engineering from the University of Memphis. His postdoctoral work has included stints in academic research as well as consulting and leadership positions with industry startups in India and in Silicon Valley, California. Saravanamuthu’s research work has been primarily in the use of Semantic Web ontologies for a) annotation and extraction of knowledge from unstructured text, b) the integration of complex, heterogeneous data from multiple sources, and c) the use of intelligent reasoning strategies to infer high-level knowledge from the integrated data. In the area of biomedical informatics, his research projects have used ontology-based data integration and reasoning to uncover novel associations between genotypic variance and phenotypic diversity. At DBMI, he uses machine learning techniques on clinical data of patients diagnosed with Phelan McDermid Syndrome, a rare syndromic variant of Autism Spectrum Disorder. Saravanamuthu works with patient self-reported outcomes data and clinical notes from electronic health records to identify patient subtypes based on phenotype profiles, refine ontological definitions of patient symptoms and conditions, and advance the knowledge about Phelan McDermid Syndrome.

Phelan-McDermid syndrome data network: Integrating patient reported outcomes with clinical notes and curated genetic reports.
Authors: Kothari C, Wack M, Hassen-Khodja C, Finan S, Savova G, O'Boyle M, Bliss G, Cornell A, Horn EJ, Davis R, Jacobs J, Kohane I, Avillach P.
Am J Med Genet B Neuropsychiatr Genet
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A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey.
Authors: Patel CJ, Pho N, McDuffie M, Easton-Marks J, Kothari C, Kohane IS, Avillach P.
Sci Data
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Conceptual Knowledge Discovery in Databases for Drug Combinations Predictions in Malignant Melanoma.
Authors: Regan K, Raje S, Saravanamuthu C, Payne PR.
Stud Health Technol Inform
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A Metadata based Knowledge Discovery Methodology for Seeding Translational Research.
Authors: Kothari CR, Payne PR.
Stud Health Technol Inform
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Evolutionary characters, phenotypes and ontologies: curating data from the systematic biology literature.
Authors: Dahdul WM, Balhoff JP, Engeman J, Grande T, Hilton EJ, Kothari C, Lapp H, Lundberg JG, Midford PE, Vision TJ, Westerfield M, Mabee PM.
PLoS One
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Phenex: ontological annotation of phenotypic diversity.
Authors: Balhoff JP, Dahdul WM, Kothari CR, Lapp H, Lundberg JG, Mabee P, Midford PE, Westerfield M, Vision TJ.
PLoS One
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