Denis Agniel
Denis Agniel, Ph.D.
Lecturer on Biomedical Informatics, Part-time

Denis Agniel received his PhD from the Harvard School of Public Health under the supervision of Tianxi Cai.  Agniel’s research was focused on statistical methods for complex phenotypes where diverse measurements are required to accurately capture the multidimensionality of disorders. In this work, he used semi- and non-parametric methods to, for example, answer questions relating to genetic risk for multiple autoimmune diseases or detect genetic variants affecting HIV disease progression. His current research is primarily focused in three areas: (1) Using statistical methods for producing accurate data-driven phenotypes for heterogeneous neuropsychiatric disorders when true disease phenotypes are unknown. Of particular interest is incorporating longitudinal and time-to-event information into phenotype classification. (2) Understanding the impact of interdisciplinarity on translational science and, in particular, using large bibliometric databases to answer questions such as, "Do interdisciplinary teams produce more translational research?" (3) Ranging across a number of statistical areas such as resampling techniques and using non-parametric functional techniques to succinctly summarize longitudinal data for the purposes of testing and treatment selection.

Overt Perceived Discrimination and Racial Microaggressions and their Association with Health Risk Behaviors among a Sample of Urban American Indian/Alaska Native Adolescents.
Authors: Dickerson DL, Brown RA, Klein DJ, Agniel D, Johnson C, D'Amico EJ.
J Racial Ethn Health Disparities
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Systemic nature of spinal muscular atrophy revealed by studying insurance claims.
Authors: Lipnick SL, Agniel DM, Aggarwal R, Makhortova NR, Finlayson SG, Brocato A, Palmer N, Darras BT, Kohane I, Rubin LL.
PLoS One
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An Integrated Approach to Measuring Sexual Orientation Disparities in Women's Access to Health Services: A National Health Interview Survey Application.
Authors: MacCarthy S, Martino SC, Burkhart Q, Beckett MK, Schuster MA, Quigley DD, Ng JH, Agniel D, Elliott MN.
LGBT Health
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Inpatient care experiences differ by preferred language within racial/ethnic groups.
Authors: Quigley DD, Elliott MN, Hambarsoomian K, Wilson-Frederick SM, Lehrman WG, Agniel D, Ng JH, Goldstein EH, Giordano LA, Martino SC.
Health Serv Res
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National racial/ethnic and geographic disparities in experiences with health care among adult Medicaid beneficiaries.
Authors: Martino SC, Mathews M, Agniel D, Orr N, Wilson-Frederick S, Ng JH, Ormson AE, Elliott MN.
Health Serv Res
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Unveiling an 'invisible population': health, substance use, sexual behavior, culture, and discrimination among urban American Indian/Alaska Native adolescents in California.
Authors: D'Amico EJ, Dickerson DL, Brown RA, Klein DJ, Agniel D, Johnson C.
Ethn Health
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Doubly robust matching estimators for high dimensional confounding adjustment.
Authors: Antonelli J, Cefalu M, Palmer N, Agniel D.
Biometrics
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Biases in electronic health record data due to processes within the healthcare system: retrospective observational study.
Authors: Agniel D, Kohane IS, Weber GM.
BMJ
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Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study.
Authors: Brat GA, Agniel D, Beam A, Yorkgitis B, Bicket M, Homer M, Fox KP, Knecht DB, McMahill-Walraven CN, Palmer N, Kohane I.
BMJ
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Developing adaptive interventions for adolescent substance use treatment settings: protocol of an observational, mixed-methods project.
Authors: Grant S, Agniel D, Almirall D, Burkhart Q, Hunter SB, McCaffrey DF, Pedersen ER, Ramchand R, Griffin BA.
Addict Sci Clin Pract
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