Sian Owen
Sian Victoria Owen, Ph.D.
Research Fellow in Biomedical Informatics
Mentor: Michael Baym, PhD

Sian Owen completed her PhD and a short postdoctoral fellowship at the University of Liverpool, UK, in the group of Professor Jay Hinton. Owen's research explored the biological contribution of temperate bacteriophages to an emerging variant of Salmonella enterica serovar Typhimurium that is associated with an epidemic of bloodstream infections in sub-Saharan Africa. She is currently working in the Baym Lab in the Department of Biomedical Informatics and the Laboratory of Systems Pharmacology using experimental evolution and computational approaches to study the phenomenon of antibiotic resistance in bacteria.

Role of a single noncoding nucleotide in the evolution of an epidemic African clade of Salmonella.
Authors: Hammarlöf DL, Kröger C, Owen SV, Canals R, Lacharme-Lora L, Wenner N, Schager AE, Wells TJ, Henderson IR, Wigley P, Hokamp K, Feasey NA, Gordon MA, Hinton JCD.
Proc Natl Acad Sci U S A
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Public health surveillance in the UK revolutionises our understanding of the invasive Salmonella Typhimurium epidemic in Africa.
Authors: Ashton PM, Owen SV, Kaindama L, Rowe WPM, Lane CR, Larkin L, Nair S, Jenkins C, de Pinna EM, Feasey NA, Hinton JCD, Dallman TJ.
Genome Med
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Direct characterization of the native structure and mechanics of cyanobacterial carboxysomes.
Authors: Faulkner M, Rodriguez-Ramos J, Dykes GF, Owen SV, Casella S, Simpson DM, Beynon RJ, Liu LN.
Nanoscale
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Characterization of the Prophage Repertoire of African Salmonella Typhimurium ST313 Reveals High Levels of Spontaneous Induction of Novel Phage BTP1.
Authors: Owen SV, Wenner N, Canals R, Makumi A, Hammarlöf DL, Gordon MA, Aertsen A, Feasey NA, Hinton JC.
Front Microbiol
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What's in a Name? Species-Wide Whole-Genome Sequencing Resolves Invasive and Noninvasive Lineages of Salmonella enterica Serotype Paratyphi B.
Authors: Connor TR, Owen SV, Langridge G, Connell S, Nair S, Reuter S, Dallman TJ, Corander J, Tabing KC, Le Hello S, Fookes M, Doublet B, Zhou Z, Feltwell T, Ellington MJ, Herrera S, Gilmour M, Cloeckaert A, Achtman M, Parkhill J, Wain J, De Pinna E, Weill FX, Peters T, Thomson N.
MBio
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RNA-seq Brings New Insights to the Intra-Macrophage Transcriptome of Salmonella Typhimurium.
Authors: Srikumar S, Kröger C, Hébrard M, Colgan A, Owen SV, Sivasankaran SK, Cameron AD, Hokamp K, Hinton JC.
PLoS Pathog
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