Tianx Cai
Tianxi Cai, ScD
Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

Tianxi Cai is a major player in developing analytical tools for EHR phenotyping and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded BD2K PIC-SURE Center of Excellence and N-GRID Center for Excellence in Genomic Science to study neuropsychiatric disease at DBMI. In addition to her collaborative work, Cai's research lab in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health develops novel statistical methods for personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Automated feature selection of predictors in electronic medical records data.
Authors: Gronsbell J, Minnier J, Yu S, Liao K, Cai T.
Biometrics
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Variance components genetic association test for zero-inflated count outcomes.
Authors: Goodman MO, Chibnik L, Cai T.
Genet Epidemiol
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Use of natural language processing in electronic medical records to identify pregnant women with suicidal behavior: towards a solution to the complex classification problem.
Authors: Zhong QY, Mittal LP, Nathan MD, Brown KM, Knudson González D, Cai T, Finan S, Gelaye B, Avillach P, Smoller JW, Karlson EW, Cai T, Williams MA.
Eur J Epidemiol
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Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes.
Authors: Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T.
Sci Data
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Distinct Proteomic Signatures in 16 HDL (High-Density Lipoprotein) Subspecies.
Authors: Furtado JD, Yamamoto R, Melchior JT, Andraski AB, Gamez-Guerrero M, Mulcahy P, He Z, Cai T, Davidson WS, Sacks FM.
Arterioscler Thromb Vasc Biol
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Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.
Authors: Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Stroke
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A phenotyping algorithm to identify acute ischemic stroke accurately from a national biobank: the Million Veteran Program.
Authors: Imran TF, Posner D, Honerlaw J, Vassy JL, Song RJ, Ho YL, Kittner SJ, Liao KP, Cai T, O'Donnell CJ, Djousse L, Gagnon DR, Gaziano JM, Wilson PW, Cho K.
Clin Epidemiol
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Nonparametric Maximum Likelihood Estimators of Time-Dependent Accuracy Measures for Survival Outcome Under Two-Stage Sampling Designs.
Authors: Liu D, Cai T, Lok A, Zheng Y.
J Am Stat Assoc
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Using a surrogate marker for early testing of a treatment effect.
Authors: Parast L, Cai T, Tian L.
Biometrics
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Decreased Total Iron Binding Capacity May Correlate with Ruptured Intracranial Aneurysms.
Authors: Can A, Lai PMR, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Sci Rep
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