Tiziana Sanavia, Ph.D.
Tiziana Sanavia, Ph.D.
Research Fellow in Biomedical Informatics
Mentor: Peter Park, PhD

Tiziana Sanavia received her PhD in Information Engineering (Bioengineering) from University of Padova with a thesis entitled, “Biomarker lists stability in genomic studies: analysis and improvement by prior biological knowledge integration into the learning process.” She was a postdoctoral fellow at the Department of Information Engineering at University of Padova from 2012 to 2016, focused on the integration of biological information in the analysis of high-throughput microarray and sequencing data. From April 2012 to March 2013 she was also a visiting scholar in the Computational Biology and Informatics Laboratory of Christian J. Stoeckert, Perelman School of Medicine at University of Pennsylvania. There she acquired new expertise in sequencing data analysis (RNA-seq for gene expression, bisulfite sequencing and Chip-seq for epigenomic data) and focused on studies of cellular development and differentiation of pancreatic cells. In 2014 she won 2-year funding for a senior postdoctoral fellowship from the University of Padova with the research project “Integrative epigenomic and genomic computational methods for high-throughput sequencing data.” She joined the Park Lab as a research fellow in April 2016, focusing on the analysis of whole genome/exome sequencing data.

ß-Arrestin-1 expression and epithelial-to-mesenchymal transition in laryngeal carcinoma.
Authors: Marioni G, Nicolè L, Cappellesso R, Marchese-Ragona R, Fasanaro E, Di Carlo R, La Torre FB, Nardello E, Sanavia T, Ottaviano G, Fassina A.
Int J Biol Markers
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Synaptotagmin 4 Regulates Pancreatic ß Cell Maturation by Modulating the Ca2+ Sensitivity of Insulin Secretion Vesicles.
Authors: Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ, Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G.
Dev Cell
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MiR-21 over-expression and Programmed Cell Death 4 down-regulation features malignant pleural mesothelioma.
Authors: Nicolè L, Cappellesso R, Sanavia T, Guzzardo V, Fassina A.
Oncotarget
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DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma.
Authors: Ferraresso S, Aricò A, Sanavia T, Da Ros S, Milan M, Cascione L, Comazzi S, Martini V, Giantin M, Di Camillo B, Mazzariol S, Giannuzzi D, Marconato L, Aresu L.
Sci Rep
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Intersection of diverse neuronal genomes and neuropsychiatric disease: The Brain Somatic Mosaicism Network.
Authors: McConnell MJ, Moran JV, Abyzov A, Akbarian S, Bae T, Cortes-Ciriano I, Erwin JA, Fasching L, Flasch DA, Freed D, Ganz J, Jaffe AE, Kwan KY, Kwon M, Lodato MA, Mills RE, Paquola ACM, Rodin RE, Rosenbluh C, Sestan N, Sherman MA, Shin JH, Song S, Straub RE, Thorpe J, Weinberger DR, Urban AE, Zhou B, Gage FH, Lehner T, Senthil G, Walsh CA, Chess A, Courchesne E, Gleeson JG, Kidd JM, Park PJ, Pevsner J, Vaccarino FM.
Science
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Oncofetal gene SALL4 and prognosis in cancer: A systematic review with meta-analysis.
Authors: Nicolè L, Sanavia T, Veronese N, Cappellesso R, Luchini C, Dabrilli P, Fassina A.
Oncotarget
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A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis.
Authors: Noren DP, Long BL, Norel R, Rrhissorrakrai K, Hess K, Hu CW, Bisberg AJ, Schultz A, Engquist E, Liu L, Lin X, Chen GM, Xie H, Hunter GA, Boutros PC, Stepanov O, Norman T, Friend SH, Stolovitzky G, Kornblau S, Qutub AA.
PLoS Comput Biol
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Inferring causal molecular networks: empirical assessment through a community-based effort.
Authors: Hill SM, Heiser LM, Cokelaer T, Unger M, Nesser NK, Carlin DE, Zhang Y, Sokolov A, Paull EO, Wong CK, Graim K, Bivol A, Wang H, Zhu F, Afsari B, Danilova LV, Favorov AV, Lee WS, Taylor D, Hu CW, Long BL, Noren DP, Bisberg AJ, Mills GB, Gray JW, Kellen M, Norman T, Friend S, Qutub AA, Fertig EJ, Guan Y, Song M, Stuart JM, Spellman PT, Koeppl H, Stolovitzky G, Saez-Rodriguez J, Mukherjee S.
Nat Methods
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Changes in microRNA expression during disease progression in patients with chronic viral hepatitis.
Authors: Sinigaglia A, Lavezzo E, Trevisan M, Sanavia T, Di Camillo B, Peta E, Scarpa M, Castagliuolo I, Guido M, Sarcognato S, Cappellesso R, Fassina A, Cardin R, Farinati F, Palù G, Barzon L.
Liver Int
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FunPat: function-based pattern analysis on RNA-seq time series data.
Authors: Sanavia T, Finotello F, Di Camillo B.
BMC Genomics
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