Jimin Guo received his PhD in Experimental Medicine from McGill University, where his work focused on signaling transduction in breast cancer. To this experience he credits his skill in “moving liquid with a micro pipettor" and extension of his vocabulary to terms such as "extravasation" and "matrix metalloproteinases."
Guo is currently serving as a joint post-doctoral fellow in the labs of Dr. Peter Kharchenko at DBMI and Dr. David Weitz at the Harvard John A. Paulson School of Engineering and Applied Sciences. His focus on how cells that look the same can do different things, or, in other words, heterogeneity of a cell population, involves preparation of aqueous droplets in inert carrier oil (similar to balsamic vinegar forming drops in olive oil in a salad dressing). This cutting-edge technology uses these droplets as miniature reaction chambers to study the genomic information of thousands of cells individually at the same time and represents the opportunities DBMI can offer to the postdoc desiring a hand in both “wet” and “dry” work.
Guo uses computational methods to reduce the tens-of-gigabyte of data to meaningful observations. And, as he says, “Unlike in graduate school, now sometimes I can drink coffee while working. Grass is indeed greener on the other side.” Furthermore, he stands tall in maintaining a strong connection to Montreal and their sports teams, an always brave position in sports-crazed Boston.
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