BMI 704 - Data Science I: Analytic Methods for Connecting the Exposome, the Genome and the Phenome

Faculty: Chirag Patel

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There is a need to prepare translational informatics researchers to repurpose large and observational biomedical population-based datasets for data-driven discovery. These datasets may include, but are not limited to observational epidemiological cohorts, medical health claims, and electronic medical records, for biomedical discovery. This course will survey the current data and methodological approaches to conduct integrative high-throughput investigation merging genomic, exposomic, and phenomic modalities to find new associations in disease and prevention.

Students will be encouraged to find publicly available population data, such as those available from the Databases of Genotypes and Phenotypes, US Centers for Disease Control and Prevention, and USAID. Students may be given sample de-identified extracts from medical claims or electronic health record datasets. Students will also be encouraged to formulate a research paper for submission to a journal or as a proceedings article.

Course available to all Harvard and MIT students with permission. Please reach out to Rebecca Fitzhugh ( for details.

Spring 1 Semester 2018 

Meeting Times: Thursday 2PM-5PM
Meeting Dates: 

  • Week 1- January 25 | Countway, Room 403                                     
  • Week 2- February 1 | Countway, Room 403        
  • Week 3- February 8 | Countway, Room 403                                    
  • Week 4- February 15 | Countway, Room 403                                    
  • Week 5- February 22 | Countway, L2-025                                  
  • Week 6- March 1 | Countway, Room 403                                    
  • Week 7- March 8 | Countway, Room 403