Tianx Cai
Tianxi Cai, ScD
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)
10 Shattuck Street, Room 434, Boston, MA 02115

Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.

DBMI Research Areas
Phenome-wide examination of comorbidity burden and multiple sclerosis disease severity.
Authors: Zhang T, Goodman M, Zhu F, Healy B, Carruthers R, Chitnis T, Weiner H, Cai T, De Jager P, Tremlett H, Xia Z.
Neurol Neuroimmunol Neuroinflamm
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Age and morphology of posterior communicating artery aneurysms.
Authors: Zhang J, Can A, Lai PMR, Mukundan S, Castro VM, Dligach D, Finan S, Yu S, Gainer VS, Shadick NA, Savova G, Murphy SN, Cai T, Weiss ST, Du R.
Sci Rep
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Association of Apolipoprotein E in Lipoprotein Subspecies With Risk of Dementia.
Authors: Koch M, DeKosky ST, Goodman M, Sun J, Furtado JD, Fitzpatrick AL, Mackey RH, Cai T, Lopez OL, Kuller LH, Mukamal KJ, Jensen MK.
JAMA Netw Open
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Developing and evaluating risk prediction models with panel current status data.
Authors: Chan S, Wang X, Jazic I, Peskoe S, Zheng Y, Cai T.
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sureLDA: A multidisease automated phenotyping method for the electronic health record.
Authors: Ahuja Y, Zhou D, He Z, Sun J, Castro VM, Gainer V, Murphy SN, Hong C, Cai T.
J Am Med Inform Assoc
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Robust and efficient semi-supervised estimation of average treatment effects with application to electronic health records data.
Authors: Cheng D, Ananthakrishnan AN, Cai T.
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Impact of ICD10 and secular changes on electronic medical record rheumatoid arthritis algorithms.
Authors: Huang S, Huang J, Cai T, Dahal KP, Cagan A, He Z, Stratton J, Gorelik I, Hong C, Cai T, Liao KP.
Rheumatology (Oxford)
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Incorporating natural language processing to improve classification of axial spondyloarthritis using electronic health records.
Authors: Zhao SS, Hong C, Cai T, Xu C, Huang J, Ermann J, Goodson NJ, Solomon DH, Cai T, Liao KP.
Rheumatology (Oxford)
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Safety and Efficacy of Tumor Necrosis Factor Antagonists in Older Patients With Ulcerative Colitis: Patient-Level Pooled Analysis of Data From Randomized Trials.
Authors: Cheng D, Cushing KC, Cai T, Ananthakrishnan AN.
Clin Gastroenterol Hepatol
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Model-free approach to quantifying the proportion of treatment effect explained by a surrogate marker.
Authors: Wang X, Parast L, Tian LU, Cai T.
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