Tianx Cai
Tianxi Cai, ScD
Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)

Tianxi Cai is a major player in developing analytical tools for EHR phenotyping and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded BD2K PIC-SURE Center of Excellence and N-GRID Center for Excellence in Genomic Science to study neuropsychiatric disease at DBMI. In addition to her collaborative work, Cai's research lab in the Department of Biostatistics at the Harvard T.H. Chan School of Public Health develops novel statistical methods for personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.


DBMI Research Areas
Assessing the value of a censored surrogate outcome.
Authors: Parast L, Tian L, Cai T.
Lifetime Data Anal
View full abstract on Pubmed
Semi-supervised estimation of covariance with application to phenome-wide association studies with electronic medical records data.
Authors: Chan SF, Hejblum BP, Chakrabortty A, Cai T.
Stat Methods Med Res
View full abstract on Pubmed
Associations of antepartum suicidal behaviour with adverse infant and obstetric outcomes.
Authors: Zhong QY, Gelaye B, Karlson EW, Avillach P, Smoller JW, Cai T, Williams MA.
Paediatr Perinat Epidemiol
View full abstract on Pubmed
f(1Feature Extraction for Phenotyping from Semantic and Knowledge Resources.
Authors: Ning W, Chan S, Beam A, Yu M, Geva A, Liao K, Mullen M, Mandl KD, Kohane I, Cai T, Yu S.
J Biomed Inform
View full abstract on Pubmed
Identifying lupus patients in electronic health records: Development and validation of machine learning algorithms and application of rule-based algorithms.
Authors: Jorge A, Castro VM, Barnado A, Gainer V, Hong C, Cai T, Cai T, Carroll R, Denny JC, Crofford L, Costenbader KH, Liao KP, Karlson EW, Feldman CH.
Semin Arthritis Rheum
View full abstract on Pubmed
Semi-supervised Validation of Multiple Surrogate Outcomes with Application to Electronic Medical Records Phenotyping.
Authors: Hong C, Liao KP, Cai T.
Biometrics
View full abstract on Pubmed
Association between aspirin dose and subarachnoid hemorrhage from saccular aneurysms: A case-control study.
Authors: Can A, Rudy RF, Castro VM, Yu S, Dligach D, Finan S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Neurology
View full abstract on Pubmed
Association of Interleukin 6 Receptor Variant With Cardiovascular Disease Effects of Interleukin 6 Receptor Blocking Therapy: A Phenome-Wide Association Study.
Authors: Cai T, Zhang Y, Ho YL, Link N, Sun J, Huang J, Cai TA, Damrauer S, Ahuja Y, Honerlaw J, Huang J, Costa L, Schubert P, Hong C, Gagnon D, Sun YV, Gaziano JM, Wilson P, Cho K, Tsao P, O'Donnell CJ, Liao KP.
JAMA Cardiol
View full abstract on Pubmed
Heroin Use Is Associated with Ruptured Saccular Aneurysms.
Authors: Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Transl Stroke Res
View full abstract on Pubmed
Pathway aggregation for survival prediction via multiple kernel learning.
Authors: Sinnott JA, Cai T.
Stat Med
View full abstract on Pubmed