Michael Baym received his PhD in Mathematics from MIT and was a postdoctoral fellow at Harvard Medical School in Systems Biology. Baym's research is centered around the problem of antibiotic resistance, at the intersection of experimental, theoretical and computational techniques. His work ranges from understanding the basic mechanisms of evolution to the development of algorithms for computation on massive biological datasets.
DBMI Research Areas
A swapped genetic code prevents viral infections and gene transfer.
Authors: Nyerges A, Vinke S, Flynn R, Owen SV, Rand EA, Budnik B, Keen E, Narasimhan K, Marchand JA, Baas-Thomas M, Liu M, Chen K, Chiappino-Pepe A, Hu F, Baym M, Church GM.
Nature
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Nature
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Mycobacterial nucleoid-associated protein Lsr2 is required for productive mycobacteriophage infection.
Authors: Dulberger CL, Guerrero-Bustamante CA, Owen SV, Wilson S, Wuo MG, Garlena RA, Serpa LA, Russell DA, Zhu J, Braunecker BJ, Squyres GR, Baym M, Kiessling LL, Garner EC, Rubin EJ, Hatfull GF.
Nat Microbiol
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Nat Microbiol
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Lineage abundance estimation for SARS-CoV-2 in wastewater using transcriptome quantification techniques.
Authors: Baaijens JA, Zulli A, Ott IM, Nika I, van der Lugt MJ, Petrone ME, Alpert T, Fauver JR, Kalinich CC, Vogels CBF, Breban MI, Duvallet C, McElroy KA, Ghaeli N, Imakaev M, Mckenzie-Bennett MF, Robison K, Plocik A, Schilling R, Pierson M, Littlefield R, Spencer ML, Simen BB, Hanage WP, Grubaugh ND, Peccia J, Baym M.
Genome Biol
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Genome Biol
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Decreased thermal niche breadth as a trade-off of antibiotic resistance.
The bacterial toxin colibactin triggers prophage induction.
Prophages encode phage-defense systems with cognate self-immunity.
Authors: Owen SV, Wenner N, Dulberger CL, Rodwell EV, Bowers-Barnard A, Quinones-Olvera N, Rigden DJ, Rubin EJ, Garner EC, Baym M, Hinton JCD.
Cell Host Microbe
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Cell Host Microbe
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Variant abundance estimation for SARS-CoV-2 in wastewater using RNA-Seq quantification.
Authors: Baaijens JA, Zulli A, Ott IM, Petrone ME, Alpert T, Fauver JR, Kalinich CC, Vogels CBF, Breban MI, Duvallet C, McElroy K, Ghaeli N, Imakaev M, Mckenzie-Bennett M, Robison K, Plocik A, Schilling R, Pierson M, Littlefield R, Spencer M, Simen BB, Hanage WP, Grubaugh ND, Peccia J, Baym M.
medRxiv
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medRxiv
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Identification of a pathway for electron uptake in Shewanella oneidensis.
Authors: Rowe AR, Salimijazi F, Trutschel L, Sackett J, Adesina O, Anzai I, Kugelmass LH, Baym MH, Barstow B.
Commun Biol
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Commun Biol
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Perfect as the enemy of good: tracing transmissions with low-sensitivity tests to mitigate SARS-CoV-2 outbreaks.
Simplitigs as an efficient and scalable representation of de Bruijn graphs.
Research and Administrative Coordinator, DBMI, Harvard Medical School