Kun-Hsing Yu, MD, PhD
Kun-Hsing Yu, MD, PhD
Assistant Professor of Biomedical Informatics, Harvard Medical School

Kun-Hsing "Kun" Yu received his PhD in Biomedical Informatics and PhD Minor in Computer Science from Stanford University, and he obtained his MD from National Taiwan University, Taiwan. His research focuses on the integration of quantitative histopathology image patterns with multi-omics (genomics, epigenomics, transcriptomics, and proteomics) profiles to advance cancer research and clinical practice. His team has developed fully-automated algorithms to analyze whole-slide histopathology images at scale, discovered the molecular mechanisms underpinning the microscopic phenotypes of tumor cells, and identified novel cellular morphologies for patient prognosis. His research interests include quantitative pathology, machine learning, and translational bioinformatics.

DBMI Research Areas
DBMI Courses
Current Postdoctoral Fellowship Opportunities
Reproducible Machine Learning Methods for Lung Cancer Detection Using Computed Tomography Images: Algorithm Development and Validation.
Authors: Yu KH, Lee TM, Yen MH, Kou SC, Rosen B, Chiang JH, Kohane IS.
J Med Internet Res
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Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks.
Authors: Yu KH, Wang F, Berry GJ, Ré C, Altman RB, Snyder M, Kohane IS.
J Am Med Inform Assoc
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Examining the Use of Real-World Evidence in the Regulatory Process.
Authors: Beaulieu-Jones BK, Finlayson SG, Yuan W, Altman RB, Kohane IS, Prasad V, Yu KH.
Clin Pharmacol Ther
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Autoimmune Effects of Lung Cancer Immunotherapy Revealed by Data-Driven Analysis on a Nationwide Cohort.
Authors: Yang S, Yu KH, Palmer N, Fox K, Kou SC, Kohane IS.
Clin Pharmacol Ther
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Deep learning in rare disease. Detection of tubers in tuberous sclerosis complex.
Authors: Sánchez Fernández I, Yang E, Calvachi P, Amengual-Gual M, Wu JY, Krueger D, Northrup H, Bebin ME, Sahin M, Yu KH, Peters JM.
PLoS One
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Suicide Rates Among Adolescents and Young Adults in the United States, 2000-2017.
Authors: Miron O, Yu KH, Wilf-Miron R, Kohane IS.
JAMA
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Evaluation of Taroni et al.: Understanding Rare Diseases by MultiPLIER.
Authors: Yu KH.
Cell Syst
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Evaluation of the association of bariatric surgery with subsequent depression.
Authors: Yuan W, Yu KH, Palmer N, Stanford FC, Kohane I.
Int J Obes (Lond)
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Data-driven analyses revealed the comorbidity landscape of tuberous sclerosis complex.
Authors: Yu KH, Miron O, Palmer N, Lemos DR, Fox K, Kou SC, Sahin M, Kohane IS.
Neurology
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Framing the challenges of artificial intelligence in medicine.
Authors: Yu KH, Kohane IS.
BMJ Qual Saf
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