Kun-Hsing Yu, MD, PhD
Kun-Hsing Yu, MD, PhD
Instructor in Biomedical Informatics, Harvard Medical School — Transitioning January 2020

Kun-Hsing "Kun" Yu received his PhD in Biomedical Informatics and PhD Minor in Computer Science from Stanford University, and he obtained his MD from National Taiwan University, Taiwan. His research focuses on the integration of quantitative histopathology image patterns with multi-omics (genomics, epigenomics, transcriptomics, and proteomics) profiles to advance cancer research and clinical practice. His team has developed fully-automated algorithms to analyze whole-slide histopathology images at scale, discovered the molecular mechanisms underpinning the microscopic phenotypes of tumor cells, and identified novel cellular morphologies for patient prognosis. His research interests include quantitative pathology, machine learning, and translational bioinformatics.

DBMI Research Areas
DBMI Courses
Current Postdoctoral Fellowship Opportunities
Association of Omics Features with Histopathology Patterns in Lung Adenocarcinoma.
Authors: Yu KH, Berry GJ, Rubin DL, Ré C, Altman RB, Snyder M.
Cell Syst
View full abstract on Pubmed
Promoting human rights through science.
Authors: Segal L, Chow RD, Kumar B, Nguyen J, Yu KH, Chen J, Polat EO, Porter KE, Kelly-Irving M, Bimpe I, Winter KA, Zeng R, Ahmed M, Saalman DR, James JI, Kosinski M, White ER, Oda FS, Bretscher H, Hamel P, Negi S, Jawaid A.
Science
View full abstract on Pubmed
Omics AnalySIs System for PRecision Oncology (OASISPRO): A Web-based Omics Analysis Tool for Clinical Phenotype Prediction.
Authors: Yu KH, Fitzpatrick MR, Pappas L, Chan W, Kung J, Snyder M.
Bioinformatics
View full abstract on Pubmed
Artificial intelligence in research.
Authors: Musib M, Wang F, Tarselli MA, Yoho R, Yu KH, Andrés RM, Greenwald NF, Pan X, Lee CH, Zhang J, Dutton-Regester K, Johnston JW, Sharafeldin IM.
Science
View full abstract on Pubmed
Biomedical informatics advancing the national health agenda: the AMIA 2015 year-in-review in clinical and consumer informatics.
Authors: Roberts K, Boland MR, Pruinelli L, Dcruz J, Berry A, Georgsson M, Hazen R, Sarmiento RF, Backonja U, Yu KH, Jiang Y, Brennan PF.
J Am Med Inform Assoc
View full abstract on Pubmed
HARNESSING BIG DATA FOR PRECISION MEDICINE: INFRASTRUCTURES AND APPLICATIONS.
Authors: Yu KH, Hart SN, Goldfeder R, Zhang QC, Parker SCJ, Snyder M.
Pac Symp Biocomput
View full abstract on Pubmed
A survival guide for interdisciplinary PhD students.
Authors: Yu KH.
Nat Biotechnol
View full abstract on Pubmed
Transcriptome Profiling of Patient-Specific Human iPSC-Cardiomyocytes Predicts Individual Drug Safety and Efficacy Responses In Vitro.
Authors: Matsa E, Burridge PW, Yu KH, Ahrens JH, Termglinchan V, Wu H, Liu C, Shukla P, Sayed N, Churko JM, Shao N, Woo NA, Chao AS, Gold JD, Karakikes I, Snyder MP, Wu JC.
Cell Stem Cell
View full abstract on Pubmed
Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features.
Authors: Yu KH, Zhang C, Berry GJ, Altman RB, Ré C, Rubin DL, Snyder M.
Nat Commun
View full abstract on Pubmed
Predicting Ovarian Cancer Patients' Clinical Response to Platinum-Based Chemotherapy by Their Tumor Proteomic Signatures.
Authors: Yu KH, Levine DA, Zhang H, Chan DW, Zhang Z, Snyder M.
J Proteome Res
View full abstract on Pubmed