Concepts in Genome Analysis
This course focuses on quantitative aspects of genetics and genomics. induding computational and statistical methods of genomic analysis. We will introduce basic concepts and discuss recent progress in population and evolutionary genetics and cover principles of statistical genetics of Mendelian and complex traits. We will then introduce current genomic technologies and key algorithms in computational biology and bioinformatics. We will discuss applications of these algorithms to genome annotation and analysis of epigenomics. cancer genomics and metagenomics data. Proficiency in programming and basic knowledge of genetics and statistics will be assumed.
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Cheng-Zhong Zhang, PhD
Assistant Professor, Pathology, Harvard Medical School
Assistant Professor, Biostatistics & Computational Biology, Dana-Farber Cancer Institute