Leveraging Data and Computation to Transform Research and Improve Health

About CCB

The Core for Computational Biomedicine (CCB) is a multi-disciplinary team of computational and quantitative scientists that collaborates with HMS Quad-based researchers to develop tools, platforms, and other data science and computational solutions that broadly enable biomedical discovery and innovation.

Contact us via email at ccb_help@hms.harvard.edu.

AlphaFold 3 Workshop — May 20, 2025

AlphaFold3 can generate highly accurate biomolecular structure predictions directly from amino acid and nucleic acid sequences, including structures that incorporate proteins, DNA, RNA, ligands, ions, and chemical modifications to both proteins and nucleic acids.

CCB is working with HMS Research Computing (RC) to deploy AlphaFold 3 and develop best practices. 

The O2 AlphaFold3 module provides the HMS community with access to AlphaFold 3 on the O2 high-performance computing cluster, alleviating the need for individual users to download model weights and large genetic databases (~1TB).

We will offer a joint CCB/RC hands-on workshop to the HMS O2 community on Tuesday, May 20 at 1 pm in the Countway Library, Room L1-032! A virtual option is also available.

Learn more & Register

Computational Resources

CCB has curated a collection of tools and learning material on computational topics in biomedical science: software packages, online/print textbooks, video series, websites, and databases. The resources cover general introductory material as well as advanced methods in specific areas. There are also links to resources available only to the HMS community.

Access the Resources

CCB Office Hours

Get expert help with the fundamentals of AI and Machine Learning or R and Statistics. In person Wednesdays or Zoom any day.

Schedule