Program Curriculum
The MMSc in Biomedical Informatics program is a full-time, in-person program completed over two academic years (four semesters).
In the first year, students complete a series of required and elective courses. In the second year, they undertake their thesis research full-time in the lab of their selected research mentor.
Students enrolled in the MMSc in Biomedical Informatics program must:
- be enrolled in program requirements for 4 full-time academic terms
- be enrolled in a minimum of 16 credits each semester
- not exceed 20 credits in any semester during the first year without program approval
- not enroll in coursework or credits above their 16 thesis research credits in any semester during the second year without program approval.
For full details about credit and residency requirements, please review the MMSc in Biomedical Informatics Plan of Instruction in the HMS Master's Programs Handbook.
Year 1 - Fall Semester: 16 credits
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BMI 701 Foundations of Biomedical Informatics I
4 creditsThis introductory course surveys methods in biomedical informatics, including methods and approaches used in clinical informatics, bioinformatics, imaging and population health informatics. Basic concepts, trends, and best practices in biomedical informatics and biomedical research, including research ethics, the conduct of research in medical science, and broad issues relative to the application of research to human health are covered. Students will become familiar with core biomedical informatics methodologies.
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BMI 714 Advanced Coding and Statistics for Biomedical Informatics
4 creditsThis course will teach students advanced coding and statistics needed to extract, transform and prepare data to work with various biomedical informatics pipelines and analyze the results. Topics covered include:
- Foundational statistical theory for biomedical informatics
- Advanced R with focus on implementing statistical analyses and data visualizations
- Advanced Python with focus on running machine learning pipelines
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BMI 717 Conduct and Communication of Science
2 creditsThis course will teach graduate students both important concepts and practical skills needed to perform high-quality biomedical informatics research. The course examines core principles related to the conduct of biomedical research and some of its practical applications in the field of biomedical informatics. Students will also learn to synthesize and communicate these concepts through written work and a poster presentation.
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Elective
6 creditsOutside of the set of required courses, students will have the opportunity to choose from a wide range of available courses to meet the program's elective requirements. In the first semester, students must complete a minimum of 6 credits to fulfill this requirement.
Possible elective options in the fall semester include:
- BMI 706: Data Visualization for Biomedical Applications (2 credits)
- BMI 708: Precision Medicine (2 credits)
- BMI 709: Creating Biomedical Dashboards with R Shiny (2 credits)
- Any of the pre-approved courses listed on the Program Electives Webpage.
Students will also have the opportunity to petition program approval to take courses outside of these options.
Year 1 - Spring Semester: 16 Credits
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BMI 702 Foundations of Biomedical Informatics II
4 creditsArtificial intelligence (AI) continues to transform medicine, offering cutting-edge approaches to address challenges in medical research and practice. This course covers the foundations of modern AI, including self-supervised learning, generative models, and multimodal techniques with applications to natural language processing, medical image analysis, patients’ medical records, and longitudinal data. The course aims to equip students with both a technical understanding of AI techniques and the implications of these technologies, especially in terms of model and data interpretability, integration into clinical and research workflows, human-AI interaction, and ethical considerations. Materials will be presented through lectures by faculty, readings of contemporary literature, small group research projects, and multiple practical tutorials with hands-on components.
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BMI 718 Working with Scientific Literature
2 creditsThis course will teach biomedical informatics graduate students the practical skills needed to use scientific literature in their biomedical informatics research. At the beginning of the course, students will participate in interactive lessons about literature reviews, the peer review process, and evaluating scientific literature. Then, students will read, evaluate, and present papers to their peers in an informal journal club format and in a formal presentation. In the final weeks of the course, students will learn how to write their own scientific proposals and papers that build on existing scientific literature.
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BMI 719 Design and Execution of Scientific Projects
2 creditsThis course will teach graduate students the practical skills to plan and execute a biomedical informatics research project, including: presentations, figure design, rigor and reproducibility, setting timelines, adapting to obstacles. This course is designed for students in the MMSc in Biomedical Informatics program and will prepare them for their thesis research year and thesis milestones, such as TAC meetings and progress report.
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Elective
8 creditsOutside of the set of required courses, students will have the opportunity to choose from a wide range of available courses to meet the program's elective requirements. In the second semester, students must complete a minimum of 8 credits to fulfill this requirement.
Possible elective options in the spring semester include:
- Deep Learning for Biomedical Data (2 credits)
- Single-cell analysis for Functional Genomics of Disease (2 credits)
- Creating Biomedical Dashboards Using R Shiny (2 credits)
- Health Information Technology: From Ideation to Innovation (4 credits)
- Any of the pre-approved courses listed on the Program Electives Webpage.
Students will also have the opportunity to petition program approval to take courses outside of these options.
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