Genetics are not likely to offer clinically useful predictions for elevated liver enzyme levels in patients using low dose methotrexate.
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases.
Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Association with HLA-DRß1 position 37 distinguishes juvenile dermatomyositis from adult-onset myositis.
Inferring gene regulation from stochastic transcriptional variation across single cells at steady state.
Polygenic enrichment distinguishes disease associations of individual cells in single-cell RNA-seq data.
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.
