Deep transcriptome sequencing of subgenual anterior cingulate cortex reveals cross-diagnostic and diagnosis-specific RNA expression changes in major psychiatric disorders.
IFN-? and TNF-a drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation.
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.
Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics.
Lymphocyte innateness defined by transcriptional states reflects a balance between proliferation and effector functions.
