Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation.
A practical framework and online tool for mutational signature analyses show inter-tissue variation and driver dependencies.
Author Correction: A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies.
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.
