Population-specific causal disease effect sizes in functionally important regions impacted by selection.
IFN-? and TNF-a drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation.
Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations.
Multimodally profiling memory T cells from a tuberculosis cohort identifies cell state associations with demographics, environment and disease.
The Power of Systems Biology: Insights on Lupus Nephritis from the Accelerating Medicines Partnership.
