Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis.
Leveraging blood and tissue CD4+ T cell heterogeneity at the single cell level to identify mechanisms of disease in rheumatoid arthritis.
Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population.
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.