An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery.
Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes.
The eMERGE genotype set of 83,717 subjects imputed to ~40?million variants genome wide and association with the herpes zoster medical record phenotype.
Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis.
Meta-analysis of Immunochip data of four autoimmune diseases reveals novel single-disease and cross-phenotype associations.
The transcriptional response in human umbilical vein endothelial cells exposed to insulin: a dynamic gene expression approach.
Function-based discovery of significant transcriptional temporal patterns in insulin stimulated muscle cells.
Effect of size and heterogeneity of samples on biomarker discovery: synthetic and real data assessment.
