Arjun Manrai

Arjun (Raj) Manrai, PhD

Assistant Professor of Biomedical Informatics, Harvard Medical School
Deputy Editor, NEJM AI
10 Shattuck Street #304, Boston, MA, 02115

Arjun (Raj) Manrai, PhD is an Assistant Professor in the Department of Biomedical Informatics at Harvard Medical School, where he leads a research lab that works broadly on applying machine learning and statistical modeling to improve medical decision-making. Raj is also a founding Deputy Editor of NEJM AI, the new artificial intelligence-focused journal from the publishers of the New England Journal of Medicine, and co-host of the NEJM AI Grand Rounds podcast.

Focus areas for Raj’s research group include the role of artificial intelligence in medical diagnosis, the clinical use of genomic data and blood laboratory biomarkers, inherited heart disease and kidney disease, decision making across populations, and reproducibility and safety challenges for medical artificial intelligence. His work has been published in the New England Journal of Medicine and JAMA, presented at the National Academy of Sciences, and featured in the New York Times, Wall Street Journal, and NPR.

Raj is also closely involved in the mentoring of students at Harvard College, having served for over a decade as a Resident Tutor and now member of the Senior Common Room of Leverett House. Students from the lab have won the Rhodes, PD Soros, and other awards to continue their training and research in machine learning and medicine.

Raj earned an AB in Physics from Harvard College followed by a PhD in Bioinformatics and Integrative Genomics from the Harvard-MIT Division of Health Sciences and Technology (HST).

He resides in the Boston area and outside work he can usually be found losing home dance competitions to his 2 young daughters.

DBMI Research Areas
DBMI Courses
Foundational Considerations for Artificial Intelligence Using Ophthalmic Images.
Authors: Abràmoff MD, Cunningham B, Patel B, Eydelman MB, Leng T, Sakamoto T, Blodi B, Grenon SM, Wolf RM, Manrai AK, Ko JM, Chiang MF, Char D.
Ophthalmology
View full abstract on Pubmed
Race-Free Equations for eGFR: Comparing Effects on CKD Classification.
Authors: Diao JA, Powe NR, Manrai AK.
J Am Soc Nephrol
View full abstract on Pubmed
Physicians, Probabilities, and Populations-Estimating the Likelihood of Disease for Common Clinical Scenarios.
Authors: Manrai AK.
JAMA Intern Med
View full abstract on Pubmed
Removing Race From Kidney Function Estimates-Reply.
Authors: Diao JA, Powe NR, Manrai AK.
JAMA
View full abstract on Pubmed
Harmonizing the Collection of Clinical Data on Genetic Testing Requisition Forms to Enhance Variant Interpretation in Hypertrophic Cardiomyopathy (HCM): A Study from the ClinGen Cardiomyopathy Variant Curation Expert Panel.
Authors: Morales A, Ing A, Antolik C, Austin-Tse C, Baudhuin LM, Bronicki L, Cirino A, Hawley MH, Fietz M, Garcia J, Ho C, Ingles J, Jarinova O, Johnston T, Kelly MA, Kurtz CL, Lebo M, Macaya D, Mahanta L, Maleszewski J, Manrai AK, Murray M, Richard G, Semsarian C, Thomson KL, Winder T, Ware JS, Hershberger RE, Funke BH, Vatta M.
J Mol Diagn
View full abstract on Pubmed
Comparisons of Polyexposure, Polygenic, and Clinical Risk Scores in Risk Prediction of Type 2 Diabetes.
Authors: He Y, Lakhani CM, Rasooly D, Manrai AK, Tzoulaki I, Patel CJ.
Diabetes Care
View full abstract on Pubmed
Association of 152 Biomarker Reference Intervals with All-Cause Mortality in Participants of a General United States Survey from 1999 to 2010.
Authors: Pho N, Manrai AK, Leppert JT, Chertow GM, Ioannidis JPA, Patel CJ.
Clin Chem
View full abstract on Pubmed
In Search of a Better Equation - Performance and Equity in Estimates of Kidney Function.
Authors: Diao JA, Inker LA, Levey AS, Tighiouart H, Powe NR, Manrai AK.
N Engl J Med
View full abstract on Pubmed
Clinical Implications of Removing Race From Estimates of Kidney Function.
Authors: Diao JA, Wu GJ, Taylor HA, Tucker JK, Powe NR, Kohane IS, Manrai AK.
JAMA
View full abstract on Pubmed
What about the environment? Leveraging multi-omic datasets to characterize the environment's role in human health.
Authors: Passero K, Setia-Verma S, McAllister K, Manrai A, Patel C, Hall M.
Pac Symp Biocomput
View full abstract on Pubmed