Chirag Patel, PhD

Chirag Patel, PhD

Associate Professor of Biomedical Informatics

10 Shattuck Street, Boston, MA 02115

Chirag Patel's long-term research goal is to address problems in human health and disease by developing computational and bioinformatics methods to reproducibly and efficiently reason over high-throughput data streams spanning molecules to populations. Patel's group aims to dissect inter-individual differences in human phenomes through strategies that integrate data sources that capture the comprehensive clinical experience (e.g., through the electronic medical record), the complex phenomena of environmental exposure (e.g., high-throughput measures of the exposome), and inherited genomic variation. He received his doctorate in biomedical informatics from Stanford University.


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Dissecting Genetic and Environmental Determinants of Plasma Molecular Signatures and Their Link to Type 2 Diabetes Risk.
Authors: Sevilla-González M, Wang N, Hanson PA, Bebo A, Hitchcock D, Hsu S, Westerman KE, Cromer SJ, Barry VG, Borns-Weil Y, Zhang Y, Ben-Yossef O, Patel CJ, Franceschini N, Taylor KD, Ávila-Pacheco J, Clish CB, Gertzen RE, Raffield LM, Kooperberg C, Rich SS, Dupuis J, Rotter JI, Liu CT, Meigs JB, Manning AK.
medRxiv
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Prognostic performance across Alzheimer's biomarkers, multi-modal physiological measures, and clinical history in asymptomatic individuals.
Authors: Ellis RJ, Airaud A, Jasodanand VH, Kowshik SS, Bellitti M, Kolachalama VB, Estiri H, Glymour MM, Dufouil C, Sperling RA, Bennett DA, Patel CJ.
medRxiv
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Quantifying diagnostic signal decay in dementia: a national study of Medicare hospitalization data.
Authors: Spoto F, Tian J, Hügel J, Ortega DT, Ritchie CS, Blacker D, Dominici F, Patel CJ, Mork D, Estiri H.
Alzheimers Dement
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Specification curve analysis of the TEDDY study reveals large variation in microbiome-based T1D predictive performance.
Authors: Zimmerman S, Tierney BT, Nguyen VK, Kostic AD, Patel CJ.
Nat Commun
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Quantitative Exposomics Targeting over 200 Toxicants and Key Biomarkers at the Picomolar Level.
Authors: Gu Y, Feuerstein ML, Lloyd DT, Patel CJ, Johnson CH, Warth B.
Environ Sci Technol
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Developing a Spatiotemporal Repository of Extreme Heat and Cold Exposure in the United States for Precision Public Health Research.
Authors: Fard P, Hügel J, Keivabu RC, Dominici F, Zagheni E, Estiri H, Patel CJ.
Environ Sci Technol
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AHA PREVENT Equations and Cardiovascular Disease Risk in Diverse Health Care Populations.
Authors: Cho SMJ, Levin M, Chen R, Samarakoon R, Judy R, Hartmann K, Postupaka D, Viscosi V, Farber-Eger E, Fahed AC, Honigberg MC, Patel CJ, Hornsby W, Wells QS, Damrauer SM, Do R, Natarajan P.
J Am Coll Cardiol
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Human Plasma Proteomics Links Modifiable Lifestyle Exposome to Disease Risk.
Authors: Isaac S, Ellis RJ, Gusev A, Murthy VL, Udler MS, Patel CJ.
medRxiv
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Uncertainty in the estimated effects of statin initiation on risk of dementia: using a multiverse analysis to assess sources of variability.
Authors: Ferguson EL, Zimmerman SC, Jiang C, Choi M, Meyers TJ, Hoffmann TJ, Gilsanz P, Wang J, Oni-Orisan A, Whitmer RA, Risch N, Krauss RM, Patel CJ, Schaefer CA, Glymour MM.
Eur J Epidemiol
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Precision nutrition for cardiometabolic diseases.
Authors: Guasch-Ferré M, Wittenbecher C, Palmnäs M, Ben-Yacov O, Blaak EE, Dahm CC, Fall T, Heitmann BL, Licht TR, Löf M, Loos R, Patel CJ, Quarta C, Redman LM, Segal E, Segata N, Snyder M, Sun Q, Tobias DK, Hu FB, Franks PW, Landberg R, Sargent JL, Merino J.
Nat Med
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