Daniel Balick

Daniel Balick, PhD

Instructor in Biomedical Informatics

Sunyaev Lab

Publications

A field theoretic approach to non-equilibrium population genetics in the strong selection regime.

Authors: Balick DJ.
bioRxiv 2023-01-19
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Overcoming constraints on the detection of recessive selection in human genes from population frequency data.

Authors: Balick DJ, Jordan DM, Sunyaev S, Do R.
Am J Hum Genet 2022-01-06
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Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy.

Authors: Radke DW, Sul JH, Balick DJ, Akle S, Green RC, Sunyaev SR.
Genome Res 2021-06-01
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Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK Biobank.

Authors: Vy HMT, Jordan DM, Balick DJ, Do R.
PLoS Genet 2021-01-01
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Applicability of the Mutation-Selection Balance Model to Population Genetics of Heterozygous Protein-Truncating Variants in Humans.

Authors: Weghorn D, Balick DJ, Cassa C, Kosmicki JA, Daly MJ, Beier DR, Sunyaev SR.
Mol Biol Evol 2019-08-01
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Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection.

Authors: Schoech AP, Jordan DM, Loh PR, Gazal S, O'Connor LJ, Balick DJ, Palamara PF, Finucane HK, Sunyaev SR, Price AL.
Nat Commun 2019-02-15
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Reply to 'Selective effects of heterozygous protein-truncating variants'.

Authors: Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR.
Nat Genet 2019-01-01
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Estimating the selective effects of heterozygous protein-truncating variants from human exome data.

Authors: Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR.
Nat Genet 2017-05-01
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Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck.

Authors: Balick DJ, Do R, Cassa CA, Reich D, Sunyaev SR.
PLoS Genet 2015-08-01
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No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans.

Authors: Do R, Balick D, Li H, Adzhubei I, Sunyaev S, Reich D.
Nat Genet 2015-02-01
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