Griffin Weber
Griffin Weber, MD, PhD
Associate Professor of Medicine, Beth Israel Deaconess Medical Center
Associate Professor of Biomedical Informatics, Harvard Medical School (Secondary)

Griffin Weber directs the Biomedical Research Informatics Core (BRIC) at BIDMC. A result of his research in expertise mining and social network analysis is his invention of an open source social networking website for scientists called Profiles RNS, now used at dozens of universities across the country. It automatically mines large datasets such as PubMed, NIH ExPORTER, and the U.S. patent database to discover investigators' research areas and scientific networks. It then presents these connections using temporal, geospatial, and network visualizations. The software has numerous applications, ranging from finding individual collaborators and mentors to understanding the dynamics of an entire research community.

Weber is also an investigator on Informatics for Integrating Biology and the Bedside (i2b2), an NIH National Center for Biomedical Computing, for which he helped developed a web-based open source platform that enables a variety of functions, including queries of large clinical repositories for hypothesis testing and identification of patients for clinical trials. He also created the original prototype software for the Shared Health Research Information Network (SHRINE), which is a federated query tool that connects i2b2 databases across multiple institutions. More than 100 institutions worldwide use i2b2 and SHRINE to support clinical research.

Weber received his M.D. and Ph.D. in computer science from Harvard University in 2007. While still a student, he became the first Chief Technology Officer of Harvard Medical School and built an educational web portal that provides interactive online content to over 500 courses. His past research projects also include analyzing DNA microarrays, modeling the growth of breast cancer tumors, and creating algorithms for predicting life expectancy.

Anticoagulation after intracranial hemorrhage in brain tumors: Risk of recurrent hemorrhage and venous thromboembolism.
Authors: Carney BJ, Uhlmann EJ, Puligandla M, Mantia C, Weber GM, Neuberg DS, Zwicker JI.
Res Pract Thromb Haemost
View full abstract on Pubmed
Validation of an Electronic Health Record-Based Suicide Risk Prediction Modeling Approach Across Multiple Health Care Systems.
Authors: Barak-Corren Y, Castro VM, Nock MK, Mandl KD, Madsen EM, Seiger A, Adams WG, Applegate RJ, Bernstam EV, Klann JG, McCarthy EP, Murphy SN, Natter M, Ostasiewski B, Patibandla N, Rosenthal GE, Silva GS, Wei K, Weber GM, Weiler SR, Reis BY, Smoller JW.
JAMA Netw Open
View full abstract on Pubmed
International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium.
Authors: Brat GA, Weber GM, Gehlenborg N, Avillach P, Palmer NP, Chiovato L, Cimino J, Waitman LR, Omenn GS, Malovini A, Moore JH, Beaulieu-Jones BK, Tibollo V, Murphy SN, Yi SL, Keller MS, Bellazzi R, Hanauer DA, Serret-Larmande A, Gutierrez-Sacristan A, Holmes JJ, Bell DS, Mandl KD, Follett RW, Klann JG, Murad DA, Scudeller L, Bucalo M, Kirchoff K, Craig J, Obeid J, Jouhet V, Griffier R, Cossin S, Moal B, Patel LP, Bellasi A, Prokosch HU, Kraska D, Sliz P, Tan ALM, Ngiam KY, Zambelli A, Mowery DL, Schiver E, Devkota B, Bradford RL, Daniar M, Daniel C, Benoit V, Bey R, Paris N, Serre P, Orlova N, Dubiel J, Hilka M, Jannot AS, Breant S, Leblanc J, Griffon N, Burgun A, Bernaux M, Sandrin A, Salamanca E, Cormont S, Ganslandt T, Gradinger T, Champ J, Boeker M, Martel P, Esteve L, Gramfort A, Grisel O, Leprovost D, Moreau T, Varoquaux G, Vie JJ, Wassermann D, Mensch A, Caucheteux C, Haverkamp C, Lemaitre G, Bosari S, Krantz ID, South A, Cai T, Kohane IS.
NPJ Digit Med
View full abstract on Pubmed
Considerations for Using the Vasculature as a Coordinate System to Map All the Cells in the Human Body.
Authors: Weber GM, Ju Y, Börner K.
Front Cardiovasc Med
View full abstract on Pubmed
Clinical Concept Embeddings Learned from Massive Sources of Multimodal Medical Data.
Authors: Beam AL, Kompa B, Schmaltz A, Fried I, Weber G, Palmer N, Shi X, Cai T, Kohane IS.
Pac Symp Biocomput
View full abstract on Pubmed
Probabilistic record linkage of de-identified research datasets with discrepancies using diagnosis codes.
Authors: Hejblum BP, Weber GM, Liao KP, Palmer NP, Churchill S, Shadick NA, Szolovits P, Murphy SN, Kohane IS, Cai T.
Sci Data
View full abstract on Pubmed
Intracranial hemorrhage with direct oral anticoagulants in patients with brain tumors.
Authors: Carney BJ, Uhlmann EJ, Puligandla M, Mantia C, Weber GM, Neuberg DS, Zwicker JI.
J Thromb Haemost
View full abstract on Pubmed
Using Artificial Intelligence in an Intelligent Way to Improve Efficiency of a Heart Failure Care Team.
Authors: Weber GM.
J Card Fail
View full abstract on Pubmed
Biases in electronic health record data due to processes within the healthcare system: retrospective observational study.
Authors: Agniel D, Kohane IS, Weber GM.
BMJ
View full abstract on Pubmed
Biases introduced by filtering electronic health records for patients with "complete data".
Authors: Weber GM, Adams WG, Bernstam EV, Bickel JP, Fox KP, Marsolo K, Raghavan VA, Turchin A, Zhou X, Murphy SN, Mandl KD.
J Am Med Inform Assoc
View full abstract on Pubmed