Lucy Jung, PhD

Lucy Jung, PhD

Former Research Fellow in Biomedical Informatics
Park Lab
Mentor: Peter Park, PhD

Lucy Jung finished her PhD from Speech and Hearing program in the division of Health Science Technology at MIT. Since joining the Park lab at DBMI, she has shifted her research interest to epigenomics. Lucy has specialized in computational analysis of epigenetic data, especially for data from chromatin immunoprecipitation experiments followed by high-throughput sequencing (ChIP-seq). One of her main projects was to perform integrative analysis of various functional genomics datasets for the Drosophila modENCODE project. She also has worked closely with several experimental biologists around the Longwood area on analysis of chromatin data, on topics such as dosage compensation, Polycomb complex, and cellular reprogramming.

Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila.
Authors: Kang H, Jung YL, McElroy KA, Zee BM, Wallace HA, Woolnough JL, Park PJ, Kuroda MI.
Genes Dev
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upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks.
Authors: McElroy KA, Jung YL, Zee BM, Wang CI, Park PJ, Kuroda MI.
G3 (Bethesda)
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The histone chaperone CAF-1 safeguards somatic cell identity.
Authors: Cheloufi S, Elling U, Hopfgartner B, Jung YL, Murn J, Ninova M, Hubmann M, Badeaux AI, Euong Ang C, Tenen D, Wesche DJ, Abazova N, Hogue M, Tasdemir N, Brumbaugh J, Rathert P, Jude J, Ferrari F, Blanco A, Fellner M, Wenzel D, Zinner M, Vidal SE, Bell O, Stadtfeld M, Chang HY, Almouzni G, Lowe SW, Rinn J, Wernig M, Aravin A, Shi Y, Park PJ, Penninger JM, Zuber J, Hochedlinger K.
Nature
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Genome-Wide Analysis of Wilms' Tumor 1-Controlled Gene Expression in Podocytes Reveals Key Regulatory Mechanisms.
Authors: Kann M, Ettou S, Jung YL, Lenz MO, Taglienti ME, Park PJ, Schermer B, Benzing T, Kreidberg JA.
J Am Soc Nephrol
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Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila.
Authors: Kang H, McElroy KA, Jung YL, Alekseyenko AA, Zee BM, Park PJ, Kuroda MI.
Genes Dev
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Correspondence of Drosophila polycomb group proteins with broad H3K27me3 silent domains.
Authors: Jung YL, Kang H, Park PJ, Kuroda MI.
Fly (Austin)
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Comparative analysis of metazoan chromatin organization.
Authors: Ho JW, Jung YL, Liu T, Alver BH, Lee S, Ikegami K, Sohn KA, Minoda A, Tolstorukov MY, Appert A, Parker SC, Gu T, Kundaje A, Riddle NC, Bishop E, Egelhofer TA, Hu SS, Alekseyenko AA, Rechtsteiner A, Asker D, Belsky JA, Bowman SK, Chen QB, Chen RA, Day DS, Dong Y, Dose AC, Duan X, Epstein CB, Ercan S, Feingold EA, Ferrari F, Garrigues JM, Gehlenborg N, Good PJ, Haseley P, He D, Herrmann M, Hoffman MM, Jeffers TE, Kharchenko PV, Kolasinska-Zwierz P, Kotwaliwale CV, Kumar N, Langley SA, Larschan EN, Latorre I, Libbrecht MW, Lin X, Park R, Pazin MJ, Pham HN, Plachetka A, Qin B, Schwartz YB, Shoresh N, Stempor P, Vielle A, Wang C, Whittle CM, Xue H, Kingston RE, Kim JH, Bernstein BE, Dernburg AF, Pirrotta V, Kuroda MI, Noble WS, Tullius TD, Kellis M, MacAlpine DM, Strome S, Elgin SC, Liu XS, Lieb JD, Ahringer J, Karpen GH, Park PJ.
Nature
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Impact of sequencing depth in ChIP-seq experiments.
Authors: Jung YL, Luquette LJ, Ho JW, Ferrari F, Tolstorukov M, Minoda A, Issner R, Epstein CB, Karpen GH, Kuroda MI, Park PJ.
Nucleic Acids Res
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"Jump start and gain" model for dosage compensation in Drosophila based on direct sequencing of nascent transcripts.
Authors: Ferrari F, Plachetka A, Alekseyenko AA, Jung YL, Ozsolak F, Kharchenko PV, Park PJ, Kuroda MI.
Cell Rep
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Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters".
Authors: Ferrari F, Jung YL, Kharchenko PV, Plachetka A, Alekseyenko AA, Kuroda MI, Park PJ.
Science
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