Luke Jen O’Connor received his Ph.D. from the Bioinformatics and Integrative Genomics (BIG) program at Harvard Medical School in 2019, and he was a Schmidt Fellow/PI at the Broad Institute of MIT and Harvard. The O’Connor Lab focuses on the genetic architecture of common disease, on statistical methods development, and on the problem of translating genetic associations into biological insight.
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Author Correction: Distinguishing genetic correlation from causation across 52 diseases and complex traits.
Distinguishing genetic correlation from causation across 52 diseases and complex traits.
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk.
Authors: Reshef YA, Finucane HK, Kelley DR, Gusev A, Kotliar D, Ulirsch JC, Hormozdiari F, Nasser J, O'Connor L, van de Geijn B, Loh PR, Grossman SR, Bhatia G, Gazal S, Palamara PF, Pinello L, Patterson N, Adams RP, Price AL.
Nat Genet
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Nat Genet
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Leveraging molecular quantitative trait loci to understand the genetic architecture of diseases and complex traits.
Authors: Hormozdiari F, Gazal S, van de Geijn B, Finucane HK, Ju CJ, Loh PR, Schoech A, Reshef Y, Liu X, O'Connor L, Gusev A, Eskin E, Price AL.
Nat Genet
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Nat Genet
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Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues.
Authors: Liu X, Finucane HK, Gusev A, Bhatia G, Gazal S, O'Connor L, Bulik-Sullivan B, Wright FA, Sullivan PF, Neale BM, Price AL.
Am J Hum Genet
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Am J Hum Genet
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