Maha Farhat
Maha Reda Farhat, M.D., MSc
Assistant Professor of Biomedical Informatics, Harvard Medical School
10 Shattuck Street #307, Boston, MA 02115

Maha Farhat  holds an MD from the McGill University Faculty of Medicine and a MSc in biostatistics from the Harvard Chan School of Public Health. She is also a practicing physician at the Massachusetts General Hospital Division of Pulmonary and Critical Care Medicine.

Dr. Farhat's research focuses on the development and application of methods for associating genotype and phenotype in infectious disease pathogens, with a strong emphasis on translation to better diagnostics and surveillance in resource-poor settings. To date, Farhat's work has focused on the pathogen Mycobacterium tuberculosis and spans the spectrum from computational analysis to field studies. She is PI and Co-Investigator on several large projects funded by NIH including the NIAID and the BD2K initiative.

DBMI Research Areas
DBMI Courses
Genetic Determinants of Drug Resistance in Mycobacterium tuberculosis and Their Diagnostic Value.
Authors: Farhat MR, Sultana R, Iartchouk O, Bozeman S, Galagan J, Sisk P, Stolte C, Nebenzahl-Guimaraes H, Jacobson K, Sloutsky A, Kaur D, Posey J, Kreiswirth BN, Kurepina N, Rigouts L, Streicher EM, Victor TC, Warren RM, van Soolingen D, Murray M.
Am J Respir Crit Care Med
View full abstract on Pubmed
Connectivity of diagnostic technologies: improving surveillance and accelerating tuberculosis elimination.
Authors: Andre E, Isaacs C, Affolabi D, Alagna R, Brockmann D, de Jong BC, Cambau E, Churchyard G, Cohen T, Delmee M, Delvenne JC, Farhat M, Habib A, Holme P, Keshavjee S, Khan A, Lightfoot P, Moore D, Moreno Y, Mundade Y, Pai M, Patel S, Nyaruhirira AU, Rocha LE, Takle J, Trébucq A, Creswell J, Boehme C.
Int J Tuberc Lung Dis
View full abstract on Pubmed
The nature, patterns, clinical outcomes, and financial impact of intraoperative adverse events in emergency surgery.
Authors: Ramly EP, Bohnen JD, Farhat MR, Razmdjou S, Mavros MN, Yeh DD, Lee J, Butler K, De Moya M, Velmahos GC, Kaafarani HM.
Am J Surg
View full abstract on Pubmed
Gyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosis.
Authors: Farhat MR, Jacobson KR, Franke MF, Kaur D, Sloutsky A, Mitnick CD, Murray M.
J Clin Microbiol
View full abstract on Pubmed
Concordance of Mycobacterium tuberculosis fluoroquinolone resistance testing: implications for treatment.
Authors: Farhat MR, Mitnick CD, Franke MF, Kaur D, Sloutsky A, Murray M, Jacobson KR.
Int J Tuberc Lung Dis
View full abstract on Pubmed
Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.
Authors: Nebenzahl-Guimaraes H, Jacobson KR, Farhat MR, Murray MB.
J Antimicrob Chemother
View full abstract on Pubmed
A phylogeny-based sampling strategy and power calculator informs genome-wide associations study design for microbial pathogens.
Authors: Farhat MR, Shapiro BJ, Sheppard SK, Colijn C, Murray M.
Genome Med
View full abstract on Pubmed
Genomic analysis identifies targets of convergent positive selection in drug-resistant Mycobacterium tuberculosis.
Authors: Farhat MR, Shapiro BJ, Kieser KJ, Sultana R, Jacobson KR, Victor TC, Warren RM, Streicher EM, Calver A, Sloutsky A, Kaur D, Posey JE, Plikaytis B, Oggioni MR, Gardy JL, Johnston JC, Rodrigues M, Tang PK, Kato-Maeda M, Borowsky ML, Muddukrishna B, Kreiswirth BN, Kurepina N, Galagan J, Gagneux S, Birren B, Rubin EJ, Lander ES, Sabeti PC, Murray M.
Nat Genet
View full abstract on Pubmed
Disturbance of respiratory muscle control in a patient with early-stage multiple sclerosis.
Authors: Farhat MR, Loring SH, Riskind P, Weinhouse G.
Eur Respir J
View full abstract on Pubmed
A comparison of early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury: a systematic review and meta-analysis.
Authors: Karvellas CJ, Farhat MR, Sajjad I, Mogensen SS, Leung AA, Wald R, Bagshaw SM.
Crit Care
View full abstract on Pubmed

Position to be filled (see Research and Administrative Assistant).