Michele Berselli is currently working as part of the 4DNucleome Data Coordination and Integration Center, focusing on the development and implementation of automated pipelines and genomic workflows in the Amazon Cloud environment.
Berselli completed his PhD in 2019 at University of Padova where he worked on the development of software and databases to investigate the secondary structures that form in nucleic acids. As a result he developed and implemented two novel algorithms (nessie and QPARSE) to detect degenerate sequence motifs that are involved in the formation of some classes of non-canonical structures. He also contributed to the development of a web-database that provides a comprehensive evaluation of G-quadruplex structures in human viruses.
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations.
Authors: Nadimpalli Kobren S, Moldovan MA, Reimers R, Traviglia D, Li X, Barnum D, Veit A, Willett J, Berselli M, Ronchetti W, Sherwood R, Krier J, Kohane IS, Sunyaev SR.
bioRxiv
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bioRxiv
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Chromoscope: interactive multiscale visualization for structural variation in human genomes.
Authors: L'Yi S, Maziec D, Stevens V, Manz T, Veit A, Berselli M, Park PJ, Glodzik D, Gehlenborg N.
Nat Methods
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Nat Methods
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Vimentin binds to G-quadruplex repeats found at telomeres and gene promoters.
Authors: Ceschi S, Berselli M, Cozzaglio M, Giantin M, Toppo S, Spolaore B, Sissi C.
Nucleic Acids Res
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Nucleic Acids Res
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BamSnap: a lightweight viewer for sequencing reads in BAM files.
The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.
Authors: Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkiran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidovic RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijevic V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton JB, Larsen DJ, Omdahl AR, McGuffin LJ, Brackenridge DA, Babbitt PC, Yunes JM, Fontana P, Zhang F, Zhu S, You R, Zhang Z, Dai S, Yao S, Tian W, Cao R, Chandler C, Amezola M, Johnson D, Chang JM, Liao WH, Liu YW, Pascarelli S, Frank Y, Hoehndorf R, Kulmanov M, Boudellioua I, Politano G, Di Carlo S, Benso A, Hakala K, Ginter F, Mehryary F, Kaewphan S, Björne J, Moen H, Tolvanen MEE, Salakoski T, Kihara D, Jain A, Šmuc T, Altenhoff A, Ben-Hur A, Rost B, Brenner SE, Orengo CA, Jeffery CJ, Bosco G, Hogan DA, Martin MJ, O'Donovan C, Mooney SD, Greene CS, Radivojac P, Friedberg I.
Genome Biol
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Genome Biol
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QPARSE: searching for long-looped or multimeric G-quadruplexes potentially distinctive and druggable.
G-quadruplex forming sequences in the genome of all known human viruses: A comprehensive guide.
Authors: Lavezzo E, Berselli M, Frasson I, Perrone R, Palù G, Brazzale AR, Richter SN, Toppo S.
PLoS Comput Biol
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PLoS Comput Biol
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NeSSie: a tool for the identification of approximate DNA sequence symmetries.
Eliciting the Functional Taxonomy from protein annotations and taxa.
Authors: Falda M, Lavezzo E, Fontana P, Bianco L, Berselli M, Formentin E, Toppo S.
Sci Rep
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Sci Rep
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