Shawn Norman Murphy, M.D., Ph.D.
Shawn Norman Murphy, M.D., Ph.D.
Professor of Neurology at MGH
Professor of Biomedical Informatics (Secondary)
6177247980

Shawn Murphy currently serves as the Director of Research Computing and Informatics at Partners Healthcare and Associate Director for the Laboratory of Computer Science at the Massachusetts General Hospital where he developed the Research Patient Data Registry (RPDR) for Partners Healthcare. This application, which serves over 5,000 investigators performing research using the hospital medical record, served as the test bed for his work with Zak Kohane in developing the open source Informatics for Integrating Biology and the Bedside (i2b2) software platform now operating at over 120 hospitals worldwide. Murphy’s contribution as chief architect of the i2b2 platform has served to strengthen the understanding of the metabolic and genetic underpinnings of complex diseases by developing an informatics framework to integrate data for clinical research from electronic health records. He is co-PI with Zak Kohane of the next generation platform, Patient-centered Information Commons BD2K Center of Excellence, which will integrate data sourced not only from the EHR, but also social medial, “omic” inputs, radiology reports, and environmental feeds and co-Investgiator on the PCORI-supported Accessible Research Commons for Health (ARCH) program, both of which are based at DBMI.

Extraction of Ejection Fraction from Echocardiography Notes for Constructing a Cohort of Patients having Heart Failure with reduced Ejection Fraction (HFrEF).
Authors: Wagholikar KB, Fischer CM, Goodson A, Herrick CD, Rees M, Toscano E, MacRae CA, Scirica BM, Desai AS, Murphy SN.
J Med Syst
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The Association Between Arthralgia and Vedolizumab Using Natural Language Processing.
Authors: Cai T, Lin TC, Bond A, Huang J, Kane-Wanger G, Cagan A, Murphy SN, Ananthakrishnan AN, Liao KP.
Inflamm Bowel Dis
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Elevated International Normalized Ratio Is Associated With Ruptured Aneurysms.
Authors: Can A, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Stroke
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Heroin Use Is Associated with Ruptured Saccular Aneurysms.
Authors: Can A, Castro VM, Ozdemir YH, Dagen S, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Transl Stroke Res
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Implementation of informatics for integrating biology and the bedside (i2b2) platform as Docker containers.
Authors: Wagholikar KB, Dessai P, Sanz J, Mendis ME, Bell DS, Murphy SN.
BMC Med Inform Decis Mak
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Low Serum Calcium and Magnesium Levels and Rupture of Intracranial Aneurysms.
Authors: Can A, Rudy RF, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Weiss ST, Du R.
Stroke
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Association between inflammation and systolic blood pressure in RA compared to patients without RA.
Authors: Yu Z, Kim SC, Vanni K, Huang J, Desai R, Murphy SN, Solomon DH, Liao KP.
Arthritis Res Ther
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Morphological Variables Associated With Ruptured Middle Cerebral Artery Aneurysms.
Authors: Zhang J, Can A, Mukundan S, Steigner M, Castro VM, Dligach D, Finan S, Yu S, Gainer V, Shadick NA, Savova G, Murphy S, Cai T, Wang Z, Weiss ST, Du R.
Neurosurgery
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Out-of-system Care and Recording of Patient Characteristics Critical for Comparative Effectiveness Research.
Authors: Lin KJ, Glynn RJ, Singer DE, Murphy SN, Lii J, Schneeweiss S.
Epidemiology
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Identifying Patients With High Data Completeness to Improve Validity of Comparative Effectiveness Research in Electronic Health Records Data.
Authors: Lin KJ, Singer DE, Glynn RJ, Murphy SN, Lii J, Schneeweiss S.
Clin Pharmacol Ther
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