Tianxi Cai, ScD
Professor of Biomedical Informatics, Harvard Medical School
John Rock Professor of Population and Translational Data Sciences, Harvard T.H. Chan School of Public Health
Director, Translational Data Science Center for a Learning Health System (CELEHS)
Tianxi Cai is a major player in developing analytical tools for mining EHR data and predictive modeling with biomedical data. She provides statistical leadership on several large-scale projects, including the NIH-funded Undiagnosed Diseases Network at DBMI. Cai's research lab develops novel statistical and machine learning methods for several areas including clinical trials, real world evidence, and personalized medicine using genomic and phenomic data. Cai received her ScD in Biostatistics at Harvard and was an assistant professor at the University of Washington before returning to Harvard as a faculty member in 2002.
DBMI Research Areas
Pathprinting: An integrative approach to understand the functional basis of disease.
Authors: Altschuler GM, Hofmann O, Kalatskaya I, Payne R, Ho Sui SJ, Saxena U, Krivtsov AV, Armstrong SA, Cai T, Stein L, Hide WA.
Genome Med
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Genome Med
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Modeling disease severity in multiple sclerosis using electronic health records.
Authors: Xia Z, Secor E, Chibnik LB, Bove RM, Cheng S, Chitnis T, Cagan A, Gainer VS, Chen PJ, Liao KP, Shaw SY, Ananthakrishnan AN, Szolovits P, Weiner HL, Karlson EW, Murphy SN, Savova GK, Cai T, Churchill SE, Plenge RM, Kohane IS, De Jager PL.
PLoS One
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PLoS One
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Evaluating the predictive value of biomarkers with stratified case-cohort design.
Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test.
Evaluating prognostic accuracy of biomarkers under competing risk.
Axial and reformatted four-chamber right ventricle-to-left ventricle diameter ratios on pulmonary CT angiography as predictors of death after acute pulmonary embolism.
Authors: Lu MT, Demehri S, Cai T, Parast L, Hunsaker AR, Goldhaber SZ, Rybicki FJ.
AJR Am J Roentgenol
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AJR Am J Roentgenol
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Portability of an algorithm to identify rheumatoid arthritis in electronic health records.
Authors: Carroll RJ, Thompson WK, Eyler AE, Mandelin AM, Cai T, Zink RM, Pacheco JA, Boomershine CS, Lasko TA, Xu H, Karlson EW, Perez RG, Gainer VS, Murphy SN, Ruderman EM, Pope RM, Plenge RM, Kho AN, Liao KP, Denny JC.
J Am Med Inform Assoc
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J Am Med Inform Assoc
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Model Checking Techniques for Assessing Functional Form Specifications in Censored Linear Regression Models.
Predictors of severe outcomes associated with Clostridium difficile infection in patients with inflammatory bowel disease.
Authors: Ananthakrishnan AN, Guzman-Perez R, Gainer V, Cai T, Churchill S, Kohane I, Plenge RM, Murphy S.
Aliment Pharmacol Ther
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Aliment Pharmacol Ther
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On the covariate-adjusted estimation for an overall treatment difference with data from a randomized comparative clinical trial.
