Genetic mapping across autoimmune diseases reveals shared associations and mechanisms

Matthew R. Lincoln, Noah Connally, Pierre-Paul Axisa, Christiane Gasperi, Mitja Mitrovic, David van Heel, Cisca Wijmenga, Sebo Withoff, Iris H. Jonkers, Leonid Padyukov, International Multiple Sclerosis Genetics Consortium, Stephen S. Rich, Robert R. Graham, Patrick M. Gaffney, Carl D. Langefeld, Timothy J. Vyse, David A. Hafler, Sung Chun, Shamil R. Sunyaev and Chris Cotsapas

Nature Genetics (2024). https://doi.org/10.1038/s41588-024-01732-8

Medical Artificial Intelligence and Human Values

Kun-Hsing Yu, Elizabeth Healey, Tze-Yun Leong, Isaac S. Kohane and Arjun K. Manrai

The New England Journal of Medicine (2024). https://doi.org/10.1056/NEJMra2214183

Polygenic risk scores for autoimmune related diseases are significantly different in cancer exceptional responders

Siyuan Chen, Amelia L. M. Tan, Maria C. Saad Menezes, Jenny F. Mao, Cassandra L. Perry, Margaret E. Vella, Vinayak V. Viswanadham, Shilpa Kobren, Susanne Churchill and Isaac S. Kohane

Nature Precision Journal (2024). https://doi.org/10.1038/s41698-024-00613-x

Specification curve analysis to identify heterogeneity in risk factors for dementia: findings from the UK Biobank

Renhao Luo, Dena Zeraatkar, Maria Glymour, Randall J. Ellis, Hossein Estiri and Chirag J. Patel

BMC Medicine (2024). https://doi.org/10.1186/s12916-024-03424-w 

Tracking SARS-CoV-2 variants of concern in wastewater: an assessment of nine computational tools using simulated genomic data

Steven G. Sutcliffe, Susanne A. Kraemer, Isaac Ellmen, Jennifer J. Knapp, Alyssa K. Overton, Delaney Nash, Jozef I. Nissimov, Trevor C. Charles, David Dreifuss, Ivan Topolsky, Pelin I. Baykal, Lara Fuhrmann, Kim P. Jablonski, Niko Beerenwinkel, Joshua I. Levy, Abayomi S. Olabode, Devan G. Becker, Gopi Gugan, Erin Brintnell, Art F.Y. Poon, Renan Valieris, Rodrigo D. Drummond, Alexandre Defelicibus, Emmanuel Dias-Neto, Rafael A. Rosales, Israel Tojal da Silva, Aspasia Orfanou, Fotis Psomopoulos, Nikolaos Pechlivanis, Lenore Pipes, Zihao Chen, Jasmijn A. Baaijens, Michael Baym and B. Jesse Shapiro,

Microbial Genomics (2024). https://doi.org/10.1099/mgen.0.001249