Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease.
Single-cell atlas of ABCA7 loss-of-function reveals impaired neuronal respiration via choline-dependent lipid imbalances.
Molecular hallmarks of excitatory and inhibitory neuronal resilience and resistance to Alzheimer's disease.
