The ENCODE Imputation Challenge: a critical assessment of methods for cross-cell type imputation of epigenomic profiles.
Epigenomic dissection of Alzheimer's disease pinpoints causal variants and reveals epigenome erosion.
Neuronal DNA double-strand breaks lead to genome structural variations and 3D genome disruption in neurodegeneration.
Single-cell atlas reveals correlates of high cognitive function, dementia, and resilience to Alzheimer's disease pathology.
Transcriptomic and spatial dissection of human ex vivo right atrial tissue reveals proinflammatory microvascular changes in ischemic heart disease.
Single-cell atlas of ABCA7 loss-of-function reveals impaired neuronal respiration via choline-dependent lipid imbalances.
