Griffin Weber

Griffin Weber, MD, PhD

Associate Professor of Medicine, Beth Israel Deaconess Medical Center
Associate Professor of Biomedical Informatics, Harvard Medical School (Secondary)

Griffin Weber directs the Biomedical Research Informatics Core (BRIC) at BIDMC. A result of his research in expertise mining and social network analysis is his invention of an open source social networking website for scientists called Profiles RNS, now used at dozens of universities across the country. It automatically mines large datasets such as PubMed, NIH ExPORTER, and the U.S. patent database to discover investigators' research areas and scientific networks. It then presents these connections using temporal, geospatial, and network visualizations. The software has numerous applications, ranging from finding individual collaborators and mentors to understanding the dynamics of an entire research community.

Weber is also an investigator on Informatics for Integrating Biology and the Bedside (i2b2), an NIH National Center for Biomedical Computing, for which he helped developed a web-based open source platform that enables a variety of functions, including queries of large clinical repositories for hypothesis testing and identification of patients for clinical trials. He also created the original prototype software for the Shared Health Research Information Network (SHRINE), which is a federated query tool that connects i2b2 databases across multiple institutions. More than 100 institutions worldwide use i2b2 and SHRINE to support clinical research.

Weber received his M.D. and Ph.D. in computer science from Harvard University in 2007. While still a student, he became the first Chief Technology Officer of Harvard Medical School and built an educational web portal that provides interactive online content to over 500 courses. His past research projects also include analyzing DNA microarrays, modeling the growth of breast cancer tumors, and creating algorithms for predicting life expectancy.

Mapping the Anatomy of the Human Lymphatic System.
Authors: Bustos VP, Wang R, Pardo J, Boppana A, Weber G, Itkin M, Singhal D.
J Reconstr Microsurg
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Towards cross-application model-agnostic federated cohort discovery.
Authors: Dobbins NJ, Morris M, Sadhu E, MacFadden D, Nazaire MD, Simons W, Weber G, Murphy S, Visweswaran S.
J Am Med Inform Assoc
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Vasculature segmentation in 3D hierarchical phase-contrast tomography images of human kidneys.
Authors: Jain Y, Walsh CL, Yagis E, Aslani S, Nandanwar S, Zhou Y, Ha J, Gustilo KS, Brunet J, Rahmani S, Tafforeau P, Bellier A, Weber GM, Lee PD, Börner K.
bioRxiv
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Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas Construction and Usage.
Authors: Börner K, Blood PD, Silverstein JC, Ruffalo M, Satija R, Teichmann SA, Pryhuber G, Misra RS, Purkerson J, Fan J, Hickey JW, Molla G, Xu C, Zhang Y, Weber G, Jain Y, Qaurooni D, Kong Y, Bueckle A, Herr BW.
bioRxiv
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SlowMoMan: a web app for discovery of important features along user-drawn trajectories in 2D embeddings.
Authors: Deol K, Weber GM, Yu YW.
Bioinform Adv
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The power of partnership: Exploring collaboration dynamics in U.S. transplant research.
Authors: Faria I, Montalvan A, Canizares S, Martins PN, Weber GM, Kazimi M, Eckhoff D.
Am J Surg
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A broadly applicable approach to enrich electronic-health-record cohorts by identifying patients with complete data: a multisite evaluation.
Authors: Klann JG, Henderson DW, Morris M, Estiri H, Weber GM, Visweswaran S, Murphy SN.
J Am Med Inform Assoc
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Functional Tissue Units in the Human Reference Atlas.
Authors: Bidanta S, Börner K, Herr BW, Nagy M, Gustilo KS, Bajema R, Maier L, Molontay R, Weber G.
bioRxiv
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Anatomical structures, cell types, and biomarkers of the healthy human blood vasculature.
Authors: Boppana A, Lee S, Malhotra R, Halushka M, Gustilo KS, Quardokus EM, Herr BW, Börner K, Weber GM.
Sci Data
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Generate Analysis-Ready Data for Real-world Evidence: Tutorial for Harnessing Electronic Health Records With Advanced Informatic Technologies.
Authors: Hou J, Zhao R, Gronsbell J, Lin Y, Bonzel CL, Zeng Q, Zhang S, Beaulieu-Jones BK, Weber GM, Jemielita T, Wan SS, Hong C, Cai T, Wen J, Ayakulangara Panickan V, Liaw KL, Liao K, Cai T.
J Med Internet Res
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