Lucy Jung, PhD

Lucy Jung, PhD

Former Research Fellow in Biomedical Informatics
Mentor: Peter Park, PhD

Lucy Jung finished her PhD from Speech and Hearing program in the division of Health Science Technology at MIT. Since joining the Park lab at DBMI, she has shifted her research interest to epigenomics. Lucy has specialized in computational analysis of epigenetic data, especially for data from chromatin immunoprecipitation experiments followed by high-throughput sequencing (ChIP-seq). One of her main projects was to perform integrative analysis of various functional genomics datasets for the Drosophila modENCODE project. She also has worked closely with several experimental biologists around the Longwood area on analysis of chromatin data, on topics such as dosage compensation, Polycomb complex, and cellular reprogramming.

Epigenetic profiling reveals key genes and cis-regulatory networks specific to human parathyroids.
Authors: Jung YL, Zhao W, Li I, Jain D, Epstein CB, Bernstein BE, Parangi S, Sherwood R, Robinson-Cohen C, Hsu YH, Park PJ, Mannstadt M.
Nat Commun
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Tetraspanin CD82 Associates with Trafficking Vesicle in Muscle Cells and Binds to Dysferlin and Myoferlin.
Authors: Fontelonga T, Hall AJ, Brown JL, Jung YL, Alexander MS, Dominov JA, Mouly V, Vieira N, Zatz M, Vainzof M, Gussoni E.
Adv Biol (Weinh)
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Characterizing the molecular impact of KMT2D variants on the epigenetic and transcriptional landscapes in Kabuki syndrome.
Authors: Jung YL, Hung C, Choi J, Lee EA, Bodamer O.
Hum Mol Genet
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ERa-associated translocations underlie oncogene amplifications in breast cancer.
Authors: Lee JJ, Jung YL, Cheong TC, Espejo Valle-Inclan J, Chu C, Gulhan DC, Ljungström V, Jin H, Viswanadham VV, Watson EV, Cortés-Ciriano I, Elledge SJ, Chiarle R, Pellman D, Park PJ.
Nature
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Author Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Authors: Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS, Park PJ.
Nat Genet
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Publisher Correction: Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Authors: Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS, Park PJ.
Nat Genet
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Resources and challenges for integrative analysis of nuclear architecture data.
Authors: Jung YL, Kirli K, Alver BH, Park PJ.
Curr Opin Genet Dev
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Epigenetic transcriptional reprogramming by WT1 mediates a repair response during podocyte injury.
Authors: Ettou S, Jung YL, Miyoshi T, Jain D, Hiratsuka K, Schumacher V, Taglienti ME, Morizane R, Park PJ, Kreidberg JA.
Sci Adv
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Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing.
Authors: Cortés-Ciriano I, Lee JJ, Xi R, Jain D, Jung YL, Yang L, Gordenin D, Klimczak LJ, Zhang CZ, Pellman DS, Park PJ.
Nat Genet
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EED, a member of the polycomb group, is required for nephron differentiation and the maintenance of nephron progenitor cells.
Authors: Zhang L, Ettou S, Khalid M, Taglienti M, Jain D, Jung YL, Seager C, Liu Y, Ng KH, Park PJ, Kreidberg JA.
Development
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