Paul Avillach

Paul Avillach, MD, PhD

Associate Professor of Biomedical Informatics, Harvard Medical School
Assistant Professor of Pediatrics, Boston Children's Hospital
Assistant Professor in the Department of Epidemiology, Harvard T.H. Chan School of Public Health

10 Shattuck Street, Boston MA 02115

Avillach Lab

Paul Avillach  holds an MD in public health and epidemiology from the University of Bordeaux and a PhD in biomedical informatics from the University of Marseilles. Avillach's research focuses on the development of novel methods and techniques for the integration of multiple heterogeneous clinic cohorts, electronic health records data, and multiple types of genomics data to encompass biological observations. He is PI and Co-Investigator on several large projects at DBMI, including the BD2K PIC-SURE Center of Excellence, the Global Rare Diseases Registry project, the PCORI ARCH project, and the PCORI Phelan-Mcdermid Syndrome project.


DBMI Research Areas
DBMI Courses
Etiologies and diagnostic work-up of extreme macrocytosis defined by an erythrocyte mean corpuscular volume over 130°fL: A study of 109 patients.
Authors: Planche V, Georgin-Lavialle S, Avillach P, Ranque B, Pavie J, Caruba T, Darnige L, Pouchot J.
Am J Hematol
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Pilot evaluation of an automated method to decrease false-positive signals induced by co-prescriptions in spontaneous reporting databases.
Authors: Avillach P, Salvo F, Thiessard F, Miremont-Salamé G, Fourrier-Reglat A, Haramburu F, Bégaud B, Moore N, Pariente A.
Pharmacoepidemiol Drug Saf
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Signal detection of potentially drug-induced acute liver injury in children using a multi-country healthcare database network.
Authors: Ferrajolo C, Coloma PM, Verhamme KM, Schuemie MJ, de Bie S, Gini R, Herings R, Mazzaglia G, Picelli G, Giaquinto C, Scotti L, Avillach P, Pedersen L, Rossi F, Capuano A, van der Lei J, Trifiró G, Sturkenboom MC.
Drug Saf
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Urinary retinol binding protein is a marker of the extent of interstitial kidney fibrosis.
Authors: Pallet N, Chauvet S, Chassé JF, Vincent M, Avillach P, Levi C, Meas-Yedid V, Olivo-Marin JC, Nga-Matsogo D, Beaune P, Thervet E, Karras A.
PLoS One
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Characteristics and outcomes of sudden cardiac arrest during sports in women.
Authors: Marijon E, Bougouin W, Celermajer DS, Périer MC, Dumas F, Benameur N, Karam N, Lamhaut L, Tafflet M, Mustafic H, de Deus NM, Le Heuzey JY, Desnos M, Avillach P, Spaulding C, Cariou A, Prugger C, Empana JP, Jouven X.
Circ Arrhythm Electrophysiol
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Major regional disparities in outcomes after sudden cardiac arrest during sports.
Authors: Marijon E, Bougouin W, Celermajer DS, Perier MC, Benameur N, Lamhaut L, Karam N, Dumas F, Tafflet M, Prugger C, Mustafic H, Rifler JP, Desnos M, Le Heuzey JY, Spaulding CM, Avillach P, Cariou A, Empana JP, Jouven X.
Eur Heart J
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The EU-ADR Web Platform: delivering advanced pharmacovigilance tools.
Authors: Oliveira JL, Lopes P, Nunes T, Campos D, Boyer S, Ahlberg E, van Mulligen EM, Kors JA, Singh B, Furlong LI, Sanz F, Bauer-Mehren A, Carrascosa MC, Mestres J, Avillach P, Diallo G, Díaz Acedo C, van der Lei J.
Pharmacoepidemiol Drug Saf
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Design and validation of an automated method to detect known adverse drug reactions in MEDLINE: a contribution from the EU-ADR project.
Authors: Avillach P, Dufour JC, Diallo G, Salvo F, Joubert M, Thiessard F, Mougin F, Trifirò G, Fourrier-Réglat A, Pariente A, Fieschi M.
J Am Med Inform Assoc
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A reference standard for evaluation of methods for drug safety signal detection using electronic healthcare record databases.
Authors: Coloma PM, Avillach P, Salvo F, Schuemie MJ, Ferrajolo C, Pariente A, Fourrier-Réglat A, Molokhia M, Patadia V, van der Lei J, Sturkenboom M, Trifirò G.
Drug Saf
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Phenome-wide association studies on a quantitative trait: application to TPMT enzyme activity and thiopurine therapy in pharmacogenomics.
Authors: Neuraz A, Chouchana L, Malamut G, Le Beller C, Roche D, Beaune P, Degoulet P, Burgun A, Loriot MA, Avillach P.
PLoS Comput Biol
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